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Stereoselective Biotransformations as an Effective Tool for the Synthesis of Chiral Compounds with P-C Bond – Scope and Limitations of the Methods

[ Vol. 16 , Issue. 11 ]

Author(s):

Ewa Zymanczyk-Duda and Magdalena Klimek-Ochab   Pages 1408 - 1422 ( 15 )

Abstract:


This article discusses advantages and limitations of the biotransformations with enzymes and whole-cell catalysts. It reviews biocatalytic synthesis of the chiral, organophosphorus compounds of different structures and characterizes their biological importance.

Keywords:

Organophosphonates, Stereoselective biotransformations, Biocatalysts

Affiliation:

Wroclaw University of Technology, Departament of Bioorganic Chemistry, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.



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