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Recent Progress in the Synthesis and Applications of Heterocycles Derived from Enaminonitriles

[ Vol. 15 , Issue. 5 ]

Author(s):

Samir Bondock, Abd El-Gaber Tarhoni and Ahmed A. Fadda   Pages 753 - 781 ( 29 )

Abstract:


Recent progress in the synthesis and use of enaminonitriles as precursors for carbocyclic and heterocyclic compounds is reviewed. The synthetic routes for preparation of enaminonitriles are based on addition and condensation reactions. Enaminonitriles can be used as building blocks for carbocyclic, five, six, and seven-membered heterocycles as well as fused heterocyclic compounds. Biological and industrial applications of heterocycles derived from enaminonitriles are also discussed.

Keywords:

Enaminonitriles, Synthesis, Dimethylformamide-dimethylacetal, N-nucleophiles, C-nucleophiles, Heterocycles

Affiliation:

Chemistry Department, Faculty of Science, Mansoura University, ET-35516 Mansoura, Egypt.



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