Shigeru Shimada Pages 601 - 620 ( 20 )
This review overviews the advances in the chemistry of bismuth-containing heterocyclic compounds during the last decade. Some new types of bismuth-containing heterocyclic systems containing nitrogen, oxygen, sulfur and/or phosphorus in addition to bismuth have been synthesized. 5,6,7,12-Tetrahydrodibenz[c,f][1,5]azabismocine derivatives were the most extensively studied bismuthcontaining heterocyclic compounds during the last decade, and a number of new compounds were synthesized. Their application to organic synthesis has shown that they are useful as reagents for the cross-coupling reaction with organic halides and as Lewis acid catalysts. Also they were used for the fixation of CO2. Some pentavalent bismuth-containing heterocyclic compounds were found to be useful in organic synthesis. Biological activity of some of bismuth-containing heterocyclic compounds was studied and found to show antimicrobial, antibacterial, antifungal, and anticancer activities.
Bismuth, Heterocyclic Compounds, Hypervalent Compounds, Organic Synthesis, Biological Activities
National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1–1–1 Higashi, Tsukuba, Ibaraki 305–8565, Japan.