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Functional Group Interconversion Reactions in Continuous Flow Reactors

[ Vol. 25 , Issue. 19 ]

Author(s):

Alexander Leslie, Angel Maria Joseph and Marcus Baumann*   Pages 2217 - 2231 ( 15 )

Abstract:


An overview of the current uptake of continuous flow techniques for various functional group interconversion reactions is presented. Besides highlighting a variety of prominent examples and their main features, this review provides insights into specific reaction classes, such as oxidations, reductions, rearrangements as well as different C-H functionalization processes. While this review can only include key examples from the last decade, the reader will find a solid foundation of important transformations along with further references to inform and appreciate the opportunities arising from modern synthesis technologies such as flow synthesis.

Keywords:

Flow synthesis, functional group interconversion, oxidation, reduction, rearrangement, C-H functionalization.

Affiliation:

School of Chemistry, University College Dublin, D04 N2E2, Dublin, School of Chemistry, University College Dublin, D04 N2E2, Dublin, School of Chemistry, University College Dublin, D04 N2E2, Dublin

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