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Natural Flavans and (Iso)Flavanones with Anticancer Activity: A Review

[ Vol. 25 , Issue. 9 ]


Arindam Gangopadhyay*   Pages 1028 - 1046 ( 19 )


The present review describes 108 new examples of naturally occurring flavans and flavanones having cytotoxic potential, which have been reported during the period of 2005 to mid-2020. These compounds are found either as aglycones or as glycosides, comprising flavans, flavanones, isoflavanones and miscellaneous flavanones (homo- and bi-flavanones). The main topics addressed in this review are source, structure, and cytotoxic activity in detail and the structure-activity relationship.


Natural flavans and flavanones, cytotoxicity, anticancer activity, aglycones, glycosides, structure-activity relationship.


Department of Chemistry, Rampurhat College, Rampurhat, Birbhum, West Bengal

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