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p-Sulfonic Acid Calix[n]arene Catalyzed Synthesis of Bioactive Heterocycles: A Review

[ Vol. 25 , Issue. 1 ]

Author(s):

Bubun Banerjee*, Gurpreet Kaur and Navdeep Kaur   Pages 209 - 222 ( 14 )

Abstract:


Metal-free organocatalysts are becoming an important tool for the sustainable development of various bioactive heterocycles. On the other hand, during the last two decades, calix[n]arenes have been gaining considerable attention due to their wide range of applicability in the field of supramolecular chemistry. Recently, sulfonic acid functionalized calix[n] arenes are being employed as an efficient alternative catalyst for the synthesis of various bioactive scaffolds. In this review, we have summarized the catalytic efficiency of p-sulfonic acid calix[n]arenes for the synthesis of diverse, biologically promising scaffolds under various reaction conditions. There is no such review available in the literature showing the catalytic applicability of p-sulfonic acid calix[n]arenes. Therefore, it is strongly believed that this review will surely attract those researchers who are interested in this fascinating organocatalyst.

Keywords:

p-Sulfonic acid calix[n]arenes, N-heterocycles, O-heterocycles, organocatalysis, bioactivity, scaffolds.

Affiliation:

Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301, Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301, Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh-174301



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