Submit Manuscript  

Article Details


An Overview of the One-pot Synthesis of Imidazolines

[ Vol. 24 , Issue. 20 ]

Author(s):

Thaipparambil Aneeja, Sankaran Radhika, Mohan Neetha and Gopinathan Anilkumar*   Pages 2341 - 2355 ( 15 )

Abstract:


One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.

Keywords:

One-pot synthesis, imidazolines, ethylenediamine, green chemistry, imidazolones, organic compounds.

Affiliation:

School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P.O., Kottayam, Kerala, 686560, School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P.O., Kottayam, Kerala, 686560, School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P.O., Kottayam, Kerala, 686560, School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P.O., Kottayam, Kerala, 686560



Read Full-Text article