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Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles

[ Vol. 24 , Issue. 22 ]

Author(s):

Laksmikanta Adak* and Tubai Ghosh   Pages 2634 - 2664 ( 31 )

Abstract:


Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed reactions have accomplished a noteworthy development in the synthesis of heterocycles. This review highlights some remarkable achievements in the iron-catalyzed synthesis of heterocyclic compounds published in the last five years.

Keywords:

Catalysis, iron, earth-abundant transition metal, synthetic methods, five-membered heterocycles, six-membered heterocycles.

Affiliation:

Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Botanic Garden, Howrah 711103, Department of Chemistry, Jadavpur University, Raja S C Mullick Road, Jadavpur, Kolkata 700032

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