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Arylpyrazoles: Heterocyclic Scaffold of Immense Therapeutic Application

Author(s):

Garima Tripathi, Anil Kumar Singh and Abhijeet Kumar*   Pages 1 - 27 ( 27 )

Abstract:


Among the broad class of heterocycles, the N-heterocycles such as pyrazoles are scaffolds of vast medicinal values. Various drugs and other biologically active molecules are known to contain this N-heterocycles as core motifs. Specifically, arylpyrazoles have exhibited diverse range of biological activities including anti-inflammatory, anti-cancerous, antimicrobial and various others. For instance, arylpyrazoles are present as core moieties in various insecticides, fungicides and drugs such as Celebrex, Trocoxil. The present review will be highlighting the significant therapeutic importance of pyrazole derivatives developed in last few years.

Keywords:

Pyrazole, anti-inflammatory, anti-malarial, anti-cancerous, anti-viral, anti-fungal.

Affiliation:

Department of Chemistry, T. N. B. College, Tilka Manjhi Bhagalpur University, Bhagalpur, Bihar, Department of Chemistry, School of Physical Sciences, Mahatma Gandhi Central University, Bihar, Department of Chemistry, School of Physical Sciences, Mahatma Gandhi Central University, Bihar



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