Rukhsana Tabassum*, Muhammad Ashfaq* and Hiroyuki Oku Pages 1815 - 1852 ( 38 )
The quinoline moiety is a privileged scaffold among heterocyclic compounds that is an important construction motif in the fields of pharmaceutical chemistry. Quinoline molecule possesses a variety of therapeutic activities like antiviral, antimalarial, antibacterial, antitumor, anticancer, antioxidant antihypertensive, antifungal, anthelmintic, cardiotonic, anticonvulsant and anti-inflammatory. This review provides an insight into recent development in transition metal free novel and modified conventional synthetic routes to yield a wide variety of substituted quinolines.
Quinoline, quinoline derivatives, transition metal free, heterocyclic compounds, synthetic protocols, therapeutic activities.
Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, 36100, Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, 36100, Division of Molecular Science, Graduate School of Science & Engineering Gunma University, Gunma 376-8515