Submit Manuscript  

Article Details


Hypervalent Iodine Reagents in the Synthesis of Flavonoids and Related Compounds

Author(s):

Rajesh Kumar, Nitya Sharma and Om Prakash*   Pages 1 - 17 ( 17 )

Abstract:


Hypervalent iodine compounds have proved to very useful reagents to bring about various oxidative transformations including- (i) α-functionalization of carbonyl compounds, (ii) oxidation of phenols, and (iii) oxidative rearrangement of ketones and α,β-unsaturated ketones. These reactions find interesting applications in the development of newer and convenient approaches for the synthesis of flavonoids. This review focuses on the use of most common three hypervalent compounds, namely iodobenzene diacetate, [hydroxyl(tosyloxy)iodo] benzene, and [bistrifluoroacetoxy(iodo)]benzene in the synthesis of cis/trans-3-hydroxyflavanones, 3- hydroxyflavones (flavonols),flavones, isoflavones and related compounds.

Keywords:

Hypervalent iodine compounds, flavones, isoflavones, flavonols, chalcones, [hydroxyl(tosyloxy)iodo] benzene.

Affiliation:

Department of Chemistry, M.L.N. College, Yamuna Nagar-135001, Haryana, Department of Chemistry, M.L.N. College, Yamuna Nagar-135001, Haryana, Department of Chemistry, Kurukshetra University, Kurukshetra-136119, Haryana



Read Full-Text article