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Highly Selective Hydroiodination of Carbon-Carbon Double or Triple Bonds

Author(s):

Yuki Yamamoto, Shin-ichi Kawaguchi, Shintaro Kodama, Akihiro Nomoto and Akiya Ogawa*   Pages 1 - 16 ( 16 )

Abstract:


Iodine is an element that exhibits characteristic features of heavy halogen, and several compounds containing iodine constitute important synthetic intermediates due to synthetically easy manipulation. To utilize iodine units for organic synthesis, a highly regio- and stereoselective introduction of iodine to versatile building blocks is significant, and a lot of researches for the selective introduction of iodine to alkynes or alkenes have been investigated. In this review article, we describe regio- and stereoselective hydroiodination to multiple bonds of building blocks, and its synthetic applications as key intermediates to construct several important compounds in organic chemistry.

Keywords:

Hydroiodination, regio- and stereoselective synthesis, alkene and alkyne activations, green synthesis, cross-coupling, iodine reagents

Affiliation:

Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Center for Education and Research in Agricultural Innovation, Faculty of Agriculture, Saga University, Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University



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