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An Overview of Recent Advances in Biological and Pharmaceutical Developments of Fluoro-containing Drugs

[ Vol. 23 , Issue. 26 ]

Author(s):

Nader G. Khaligh*, Hanna Abbo, Salam J.J. Titinchi and Mohd R. Johan   Pages 2916 - 2944 ( 29 )

Abstract:


This review article provides a brief assessment of the biological and pharmaceutical developments of fluorinated drugs. It also discusses possible impacts on the further development of new fluoro-containing pharmaceuticals. Structural aspects of new drug-candidates currently under development and their biological properties, therapeutic potential and syntheses are critically evaluated.

Keywords:

Fluoro-containing pharmaceutical, structure-activity relationship, biological property, therapeutic potential, fluorinated organic molecules, new drug-candidates.

Affiliation:

Nanotechnology and Catalysis Research Center, Institute of Postgraduate Studies, University of Malaya, 50603 Kuala Lumpur, Department of Chemistry, College of Science, University of Basrah, Basrah, Department of Chemistry, University of the Western Cape, Cape Town, Nanotechnology and Catalysis Research Center, Institute of Postgraduate Studies, University of Malaya, 50603 Kuala Lumpur

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