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Catalytic Applications of Saccharin and its Derivatives in Organic Synthesis

[ Vol. 23 , Issue. 28 ]

Author(s):

Bubun Banerjee*, Vaishali Bhardwaj, Amninder Kaur, Gurpreet Kaur and Arvind Singh   Pages 3191 - 3205 ( 15 )

Abstract:


Saccharin (1,2-benzisothiazol-3(2H)-one-1,1-dioxide) is a very mild, cheap, commercially available, water soluble, environmentally benign and edible Brønsted acidic substance. Recently, with other utilities, saccharin and its derivatives were employed as catalysts for various organic transformations. In this review, catalytic applicability of saccharin and its derivatives under various reaction conditions is summarized.

Keywords:

Green and sustainable synthesis, metal-free organo-catalysis, saccharin, saccharin sulfonic acid, sodium saccharin, DMAPsaccharin, tetrazole-amino-saccharin.

Affiliation:

Department of Chemistry, Indus International University, Village and Post Office Bathu, District Una, Himachal Pradesh 174301, Department of Chemistry, Indus International University, Village and Post Office Bathu, District Una, Himachal Pradesh 174301, Department of Chemistry, Indus International University, Village and Post Office Bathu, District Una, Himachal Pradesh 174301, Department of Chemistry, Indus International University, Village and Post Office Bathu, District Una, Himachal Pradesh 174301, Department of Chemistry, Indus International University, Village and Post Office Bathu, District Una, Himachal Pradesh 174301

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