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Isolation, Synthesis and Medicinal Significance of Marine Pyridoacridine Alkaloids

[ Vol. 23 , Issue. 13 ]

Author(s):

Saqlain Haider, Amar G. Chittiboyina * and Ikhlas A. Khan   Pages 1469 - 1495 ( 27 )

Abstract:


Pyridoacridine alkaloids, distributed in marine organisms have emerged as an important class of compounds due to their uniqure chemical architecture, diversity and medicinal significance. These alkaloids are reported to exhibit a wide array of biological activities like anti-cancer, anti-bacterial, ant-viral, anti-fungal and anti-parasitic activities. The present review highlights the isolation, synthesis and medicinal significance of this important class of pyridoacridine alkaloids.

Keywords:

Pyridoacridine, biosynthesis, annulation, Boekelheide rearrangement, isolation, synthesis, anti-parasitic.

Affiliation:

National Center for Natural Products Research, University of Mississippi, University, MS-38677, National Center for Natural Products Research, University of Mississippi, University, MS-38677, National Center for Natural Products Research, University of Mississippi, University, MS-38677

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