Submit Manuscript  

Article Details


Phosphorus-Containing Groups Assisted Transition Metal Catalyzed C-H Activation Reactions

[ Vol. 23 , Issue. 2 ]

Author(s):

Chun-Ni Zhou, Zi-Ang Zheng, George Chang, Yuan-Chao Xiao, Yang-Huan Shen, Gen Li, Yu-Min Zhang, Wang-Ming Peng, Liang Wang* and Biao Xiao*   Pages 103 - 135 ( 33 )

Abstract:


Over the last few decades, transition metal-catalyzed direct C-H activation with the assistance of a coordinating directing group has emerged as an atom- and stepeconomical synthetic tools to transform C–H bonds into carbon-carbon or carbonheteroatom bonds. Although the strategies involving regioselective C–H cleavage assisted by various directing groups have been extensively reviewed in the literature, we now attempt to give an overview of the recent advances on phosphorus-containing functional group assisted C-H activation reactions catalyzed by transition-metal catalysts including mechanistic study and synthetic applications. The discussion is directed towards C-H olefination, C-H activation/cyclization, C-H arylation, C-H amination, C-H hydroxylation and acetoxylation as well as miscellaneous C-H activation.

Keywords:

Phosphorus, directing groups, transition metals, C-H activation, C-H bond cleavage, heterocycles.

Affiliation:

Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Department of Chemical Engineering, Waterloo Institute for Nanotechnology (WIN), University of Waterloo, 200 University Ave West ON, Waterloo, N2L 3G1, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056, Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, 8 Sanjiaohu Road, Wuhan 430056

Graphical Abstract:



Read Full-Text article