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Recent Advances in the Synthesis of Ferrocene-Based Heterocycles by Multicomponent Reactions: A Review

[ Vol. 22 , Issue. 26 ]

Author(s):

Mahsa Shojaei Yeganeh, Fatemeh Abbasi and Ali Reza Kazemizadeh*   Pages 2555 - 2575 ( 21 )

Abstract:


Heterocycles are cyclic compounds with one or more heteroatom in their structures. They have various pharmaceutical applications. Incorporation of ferrocene scaffold into heterocyclic compounds can change the chemical and physiochemical properties of compounds. Ferrocene derivatives have a significant importance in pharmaceutical sciences like antibacterial, anticancer, antifungal, antiparasitic drug candidates, etc. Multicomponent reactions lead to simple and rapid procedures for the synthesis of organic compounds with molecular diversity. Multicomponent reactions have been used widely in heterocyclic synthesis, pharmaceutical chemistry, natural product synthesis, combinatorial chemistry, and polymer chemistry in the past two decades. This review deals with the synthesis of ferrocene-based heterocycles by multicomponent reactions.

Keywords:

Multicomponent reactions, ferrocene, heterocycles, isocyanide, ferrocenecarbaldehyde, azetidine.

Affiliation:

Research Laboratory of MCRs, Department of Chemistry, Zanjan Branch, Islamic Azad University, Zanjan P.O. Box 49195-467, Research Laboratory of MCRs, Department of Chemistry, Zanjan Branch, Islamic Azad University, Zanjan P.O. Box 49195-467, Research Laboratory of MCRs, Department of Chemistry, Zanjan Branch, Islamic Azad University, Zanjan P.O. Box 49195-467

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