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Current Status and Future Developments in Synthetic Peptides

[ Vol. 22 , Issue. 20 ]

Author(s):

Bing Yu, Ankang Zhang, Min Zhang, Wenli Wang, Wenlong Li, Youqing Shen and Hailin Cong*   Pages 1951 - 1958 ( 8 )

Abstract:


Rapid developments in protein engineering, immunology and pharmaceutical research have led to immense demands for synthetic polypeptides. Several polypeptides synthesizing strategies are now available, among which solid-phase synthesis and solution- phase synthesis are especially relevant. This review pretended to compare these two synthesizing strategies with no bias, appreciate their advantages, drawbacks and limitations, and forecast their developmental trends. It also introduced several other special synthetic strategies, and their applications were presented in detail.

Keywords:

Peptide, oligopeptide, synthetic peptide, solid phase synthesis, solution phase synthesis, microwave-assisted.

Affiliation:

Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, Institute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071



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