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Recent Advances in Transition-Metal-Catalyzed Halides Formation

[ Vol. 22 , Issue. 23 ]

Author(s):

Xiaolin Shi and Dayong Shi*   Pages 2229 - 2255 ( 27 )

Abstract:


Halides, as important starting materials, construct complex structures and notable structural motifs in natural products and manufactured drugs. Transition-metalcatalyzed halides formation has emerged as a particular approach to generating organohalides, which is predictable to compete as an alternative to more established synthetic methods. This review attempts to provide different methods to catalyze the synthesis of organohalides by using different transition metals, as well as their application in synthetic chemistry.

Keywords:

Catalysis, C-X bond, halides formation, halogenated, organohalides, palladium, transition metals.

Affiliation:

CAS Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China; University of Chinese Academy of Sciences, Beijing 100049, CAS Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China; University of Chinese Academy of Sciences, Beijing 100049



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