Hashim Farooq, Denis Courtier-Murias, Ronald Soong, Wolfgang Bermel, William M. Kingery and André J. Simpson Pages 3013 - 3031 ( 19 )
High Resolution Magic Angle Spinning (HR-MAS) NMR spectroscopy is a versatile technique that provides high resolution NMR data on samples containing solutions, gels and swellable solids. In addition to providing structural information HR-MAS can also be used to investigate interfaces (for example organic structures at the solid-aqueous soil interface), processes such as swelling/ flocculation, kinetic transfer between gel/liquid phases, as well as conformation and molecular interactions in situ. As such, HRMAS has potential in a diversity of fields including organic, biological, environmental, and medical research. This manuscript focuses on the application of HR-MAS to intact natural samples. A range of 1D and 2D NMR experiments are reviewed and compared in terms of general performance on a range of samples. Therefore, this practical guide and review should be a useful reference and starting point for those wishing to apply HR-MAS NMR. While this article focuses on natural samples, common key 1D and 2D experiments are considered which may be of interest to readers with diverse research interests.
1D NMR, 2D NMR, Algae, High resolution magic angle spinning (HR-MAS), Natural samples, NMR, Soils, Worm tissue.
Department of Chemistry, University of Toronto, 1265 Military Trail, Toronto, Canada, M1C 1A4.